An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns

Rho GTPase-based signaling networks control cellular dynamics by coordinating protrusions and retractions in space and time. Here, we reveal a signaling network that generates pulses and propagating waves of cell contractions. These dynamic patterns emerge via self-organization from an activator–inh...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Graessl, Melanie, Koch, Johannes, Calderon, Abram, Kamps, Dominic, Banerjee, Soumya, Mazel, Tomáš, Schulze, Nina, Jungkurth, Jana Kathrin, Patwardhan, Rutuja, Solouk, Djamschid, Hampe, Nico, Hoffmann, Bernd, Dehmelt, Leif, Nalbant, Perihan
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716289/
https://ncbi.nlm.nih.gov/pubmed/29055010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706052
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