The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45

RecJ nucleases specifically degrade single-stranded (ss) DNA in the 5′ to 3′ direction. Archaeal RecJ is different from bacterial RecJ in sequence, domain organization, and substrate specificity. The RecJ from archaea Pyrococcus furiosus (PfuRecJ) also hydrolyzes RNA strands in the 3′ to 5′ directio...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Li, Min-Jun, Yi, Gang-Shun, Yu, Feng, Zhou, Huan, Chen, Jia-Nan, Xu, Chun-Yan, Wang, Feng-Ping, Xiao, Xiang, He, Jian-Hua, Liu, Xi-Peng
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716160/
https://ncbi.nlm.nih.gov/pubmed/30053256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx887
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