The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45

RecJ nucleases specifically degrade single-stranded (ss) DNA in the 5′ to 3′ direction. Archaeal RecJ is different from bacterial RecJ in sequence, domain organization, and substrate specificity. The RecJ from archaea Pyrococcus furiosus (PfuRecJ) also hydrolyzes RNA strands in the 3′ to 5′ directio...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Li, Min-Jun, Yi, Gang-Shun, Yu, Feng, Zhou, Huan, Chen, Jia-Nan, Xu, Chun-Yan, Wang, Feng-Ping, Xiao, Xiang, He, Jian-Hua, Liu, Xi-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716160/
https://ncbi.nlm.nih.gov/pubmed/30053256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx887
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