The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45

RecJ nucleases specifically degrade single-stranded (ss) DNA in the 5′ to 3′ direction. Archaeal RecJ is different from bacterial RecJ in sequence, domain organization, and substrate specificity. The RecJ from archaea Pyrococcus furiosus (PfuRecJ) also hydrolyzes RNA strands in the 3′ to 5′ directio...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Li, Min-Jun, Yi, Gang-Shun, Yu, Feng, Zhou, Huan, Chen, Jia-Nan, Xu, Chun-Yan, Wang, Feng-Ping, Xiao, Xiang, He, Jian-Hua, Liu, Xi-Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716160/
https://ncbi.nlm.nih.gov/pubmed/30053256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx887
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