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The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes

BACKGROUND: In eukaryotes, the CMG (CDC45, MCM, GINS) complex containing the replicative helicase MCM is a key player in DNA replication. Archaeal homologs of the eukaryotic MCM and GINS proteins have been identified but until recently no homolog of the CDC45 protein was known. Two recent developmen...

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Autori principali: Makarova, Kira S, Koonin, Eugene V, Kelman, Zvi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307487/
https://ncbi.nlm.nih.gov/pubmed/22329974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-7-7
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