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Celastrol improves self-renewal and differentiation of human tendon-derived stem cells by suppressing Smad7 through hypoxia
BACKGROUND: We aimed to evaluate the potential enhancing effect of celastrol on the stemness of human tendon-derived stem cells (hTSCs) in vitro and the underlying molecular mechanisms. METHODS: The capability of hTSC self-renewal was assessed by cell proliferation and colony formation as determined...
Shranjeno v:
| izdano v: | Stem Cell Res Ther |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715986/ https://ncbi.nlm.nih.gov/pubmed/29202812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0724-x |
| Oznake: |
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