載入...
Dual function for Tango1 in secretion of bulky cargo and in ER-Golgi morphology
Tango1 enables ER-to-Golgi trafficking of large proteins. We show here that loss of Tango1, in addition to disrupting protein secretion and ER/Golgi morphology, causes ER stress and defects in cell shape. We find that the previously observed dependence of smaller cargos on Tango1 is a secondary effe...
Na minha lista:
| 發表在: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715762/ https://ncbi.nlm.nih.gov/pubmed/29138315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711408114 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|