Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation

BACKGROUND AND PURPOSE: Streptococcus pneumoniae is the most common cause of bacterial meningitis in adults and is characterized by high lethality and substantial cognitive disabilities in survivors. Here, we have studied the capacity of an established therapeutic agent, magnesium, to improve surviv...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Hupp, Sabrina, Ribes, Sandra, Seele, Jana, Bischoff, Carolin, Förtsch, Christina, Maier, Elke, Benz, Roland, Mitchell, Timothy J, Nau, Roland, Iliev, Asparouh I
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715590/
https://ncbi.nlm.nih.gov/pubmed/28888095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14027
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