p53‐mediated regulation of bile acid disposition attenuates cholic acid‐induced cholestasis in mice

BACKGROUND AND PURPOSE: The tumour suppressor p53 is traditionally recognized as a surveillance molecule to preserve genome integrity. Recent studies have demonstrated that it contributes to metabolic diseases. Here, we investigated the role of p53 in the regulation of bile acid disposition and chol...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Chen, Pan, Li, Dongshun, Chen, Yixin, Sun, Jiahong, Fu, Kaili, Guan, Lihuan, Zhang, Huizhen, Jiang, Yiming, Li, Xi, Zeng, Xuezhen, Chen, Xiao, Huang, Min, Bi, Huichang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715589/
https://ncbi.nlm.nih.gov/pubmed/28910492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14035
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