Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy‐mediated differentiation

BACKGROUND AND PURPOSE: The poor prognosis of acute megakaryoblastic leukaemia (AMKL) means there is a need to develop novel therapeutic methods to treat this condition. It was recently shown that inducing megakaryoblasts to undergo terminal differentiation is effective as a treatment for AMKL. This...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Liu, Ting, Zhang, Zhenxing, Yu, Chunjie, Zeng, Chang, Xu, Xiaoqing, Wu, Guixian, Huang, Zan, Li, Wenhua
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715583/
https://ncbi.nlm.nih.gov/pubmed/28901537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14031
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