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Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells

All-trans retinoic acid (ATRA) is a differentiating agent for the treatment of acute promyelocytic leukemia (APL). However, the therapeutic efficacy of ATRA has limitations. Tetrandrine is a traditional Chinese medicinal herb extract with antitumor effects. In this study, we investigated the effects...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Ting, Men, Qiuxu, Wu, Guixian, Yu, Chunrong, Huang, Zan, Liu, Xin, Li, Wenhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480730/
https://ncbi.nlm.nih.gov/pubmed/25797266
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