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Checkpoint Blockade Toxicity and Immune Homeostasis in the Gastrointestinal Tract
Monoclonal antibodies targeting the regulatory immune “checkpoint” receptors CTLA-4, PD-1, and PD-L1 are now standard therapy for diverse malignancies including melanoma, lung cancer, and renal cell carcinoma. Although effective in many patients and able to induce cures in some, targeting these regu...
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| Publicado no: | Front Immunol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715331/ https://ncbi.nlm.nih.gov/pubmed/29230210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01547 |
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