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Concurrent therapy with immune checkpoint inhibitors and TNFα blockade in patients with gastrointestinal immune-related adverse events

BACKGROUND: Immune checkpoint inhibitors (ICI) have demonstrated remarkable efficacy as cancer therapeutics, however, their use remains limited due to the development of immune related adverse events (irAEs). Immune related enterocolitis (irEC) is among the most common severe irAEs leading to the di...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Badran, Yousef R., Cohen, Justine V., Brastianos, Priscilla K., Parikh, Aparna R., Hong, Theodore S., Dougan, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704680/
https://ncbi.nlm.nih.gov/pubmed/31439050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0711-0
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