Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

Subunit vaccines have been investigated in over 1000 clinical trials of cancer immunotherapy, but have shown limited efficacy. Nanovaccines may improve efficacy but have rarely been clinically translated. By conjugating molecular vaccines with Evans blue (EB) into albumin-binding vaccines (AlbiVax),...

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Udgivet i:Nat Commun
Main Authors: Zhu, Guizhi, Lynn, Geoffrey M., Jacobson, Orit, Chen, Kai, Liu, Yi, Zhang, Huimin, Ma, Ying, Zhang, Fuwu, Tian, Rui, Ni, Qianqian, Cheng, Siyuan, Wang, Zhantong, Lu, Nan, Yung, Bryant C., Wang, Zhe, Lang, Lixin, Fu, Xiao, Jin, Albert, Weiss, Ido D., Vishwasrao, Harshad, Niu, Gang, Shroff, Hari, Klinman, Dennis M., Seder, Robert A., Chen, Xiaoyuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715147/
https://ncbi.nlm.nih.gov/pubmed/29203865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02191-y
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