Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy

Subunit vaccines have been investigated in over 1000 clinical trials of cancer immunotherapy, but have shown limited efficacy. Nanovaccines may improve efficacy but have rarely been clinically translated. By conjugating molecular vaccines with Evans blue (EB) into albumin-binding vaccines (AlbiVax),...

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Publicado no:Nat Commun
Main Authors: Zhu, Guizhi, Lynn, Geoffrey M., Jacobson, Orit, Chen, Kai, Liu, Yi, Zhang, Huimin, Ma, Ying, Zhang, Fuwu, Tian, Rui, Ni, Qianqian, Cheng, Siyuan, Wang, Zhantong, Lu, Nan, Yung, Bryant C., Wang, Zhe, Lang, Lixin, Fu, Xiao, Jin, Albert, Weiss, Ido D., Vishwasrao, Harshad, Niu, Gang, Shroff, Hari, Klinman, Dennis M., Seder, Robert A., Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715147/
https://ncbi.nlm.nih.gov/pubmed/29203865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02191-y
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