Purification and functional comparison of nine human Aquaporins produced in Saccharomyces cerevisiae for the purpose of biophysical characterization

The sparse number of high-resolution human membrane protein structures severely restricts our comprehension of molecular physiology and ability to exploit rational drug design. In the search for a standardized, cheap and easily handled human membrane protein production platform, we thoroughly invest...

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Pubblicato in:Sci Rep
Autori principali: Bjørkskov, Frederik Bühring, Krabbe, Simon Lyngaa, Nurup, Casper Normann, Missel, Julie Winkel, Spulber, Mariana, Bomholt, Julie, Molbaek, Karen, Helix-Nielsen, Claus, Gotfryd, Kamil, Gourdon, Pontus, Pedersen, Per Amstrup
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715081/
https://ncbi.nlm.nih.gov/pubmed/29203835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17095-6
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