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Effect of Cyclodextrins on the Complexation and Nasal Permeation of Melatonin

The inclusion complexation of melatonin (MT) with modified cyclodextrins (CDs) was studied with an objective of improving the solubility and nasal absorption of MT. The formation of inclusion complex of MT with Hydroxypropyl βCD (HPβCD) and randomly methylated βCD (RMβCD) was characterized in soluti...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Babu, R. Jayachandra, Dayal, Pankaj, Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714811/
https://ncbi.nlm.nih.gov/pubmed/18686082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717540802006922
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