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Effect of Cyclodextrins on the Complexation and Nasal Permeation of Melatonin
The inclusion complexation of melatonin (MT) with modified cyclodextrins (CDs) was studied with an objective of improving the solubility and nasal absorption of MT. The formation of inclusion complex of MT with Hydroxypropyl βCD (HPβCD) and randomly methylated βCD (RMβCD) was characterized in soluti...
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Publicado no: | Drug Deliv |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714811/ https://ncbi.nlm.nih.gov/pubmed/18686082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717540802006922 |
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