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Triptolide protects podocytes from TGF-β-induced injury by preventing miR-30 downregulation

Triptolide is known to have a strong anti-proteinuric effect through direct protection of podocytes from injury and is used to treat glomerular diseases. However, the mechanism underlying its protective effect on podocytes remains elusive. MiR-30 family has recently been shown to be essential for st...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Yang, Qianqian, Sun, Mengjie, Chen, Ying, Lu, Yuqiu, Ye, Yuting, Song, Hui, Xu, Xiaodong, Shi, Shaolin, Wang, Jinquan
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714798/
https://ncbi.nlm.nih.gov/pubmed/29218112
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