Extendin-4 protects kidney from acute ischemia-reperfusion injury through upregulation of NRF2 signaling

This study tested the hypothesis that exendin-4 (Ex4) protects kidneys against ischemia-reperfusion (IR) injury mainly through upregulation of nuclear-factor erythroid 2-related factor 2 (Nrf2) signaling and downregulation of oxidative stress. Male-adult Sprague-Dawley rats (n=24) were equally divid...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Zhen, Yen-Yi, Yang, Chih-Chao, Hung, Chi-Chih, Lee, Chia-Chang, Lee, Chen-Chang, Wu, Chien-Hsing, Chen, Yen-Ta, Chen, Wei-Yu, Chen, Kuan-Hung, Yip, Hon-Kan, Ko, Sheung-Fat
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714764/
https://ncbi.nlm.nih.gov/pubmed/29218078
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