Sitagliptin protects rat kidneys from acute ischemia-reperfusion injury via upregulation of GLP-1 and GLP-1 receptors

AIM: Sitagliptin, an oral glucose-lowering agent, has been found to produce cardiovascular protection possibly via anti-inflammatory and anti-atherosclerotic activities of glucagon-like peptide-1 receptor (GLP-1). The aim of this study was to investigate whether sitagliptin protected the kidney func...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Chang, Meng-wei, Chen, Chih-hung, Chen, Yi-ching, Wu, Ying-chun, Zhen, Yen-yi, Leu, Steve, Tsai, Tzu-hsien, Ko, Sheung-fat, Sung, Pei-hsun, Yang, Chih-chau, Chiang, Hsin-ju, Chang, Hsueh-wen, Chen, Yen-ta, Yip, Hon-kan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571325/
https://ncbi.nlm.nih.gov/pubmed/25500876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.98
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