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Bone microenvironment has an influence on the histological response of osteosarcoma to chemotherapy: retrospective analysis and preclinical modeling

Osteosarcoma, the most common malignant primary bone tumor, is currently treated with chemotherapy and surgery. The effectiveness of chemotherapy is evaluated by means of histological analysis of tumor necrosis, known as “the Huvos score”. However, 25% of the patients initially considered good respo...

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Bibliografische gegevens
Gepubliceerd in:Am J Cancer Res
Hoofdauteurs: Crenn, Vincent, Biteau, Kevin, Amiaud, Jérôme, Dumars, Clotilde, Guiho, Romain, Vidal, Luciano, Nail, Louis-Romée Le, Heymann, Dominique, Moreau, Anne, Gouin, François, Redini, Françoise
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714759/
https://ncbi.nlm.nih.gov/pubmed/29218254
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