L-MTP-PE and zoledronic acid combination in osteosarcoma: preclinical evidence of positive therapeutic combination for clinical transfer

Osteosarcoma, the most frequent malignant primary bone tumor in pediatric patients is characterized by osteolysis promoting tumor growth. Lung metastasis is the major bad prognosis factor of this disease. Zoledronic Acid (ZA), a potent inhibitor of bone resorption is currently evaluated in phase III...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Biteau, Kevin, Guiho, Romain, Chatelais, Mathias, Taurelle, Julien, Chesneau, Julie, Corradini, Nadège, Heymann, Dominique, Redini, Françoise
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851846/
https://ncbi.nlm.nih.gov/pubmed/27152244
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