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Characterization of dFOXO binding sites upstream of the Insulin Receptor P2 promoter across the Drosophila phylogeny

The insulin/TOR signal transduction pathway plays a critical role in determining such important traits as body and organ size, metabolic homeostasis and life span. Although this pathway is highly conserved across the animal kingdom, the affected traits can exhibit important differences even between...

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Pubblicato in:PLoS One
Autori principali: Orengo, Dorcas J., Aguadé, Montserrat, Juan, Elvira
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714339/
https://ncbi.nlm.nih.gov/pubmed/29200426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188357
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