The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner

The nuclear mitotic apparatus protein, NuMA, is involved in major cellular events such as DNA damage response, apoptosis and p53-mediated growth-arrest, all of which are under the control of the nucleolus upon stress. Proteomic investigation has identified NuMA among hundreds of nucleolar proteins....

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Jayaraman, Swaathi, Chittiboyina, Shirisha, Bai, Yunfeng, Abad, Patricia C., Vidi, Pierre-Alexandre, Stauffacher, Cynthia V., Lelièvre, Sophie A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714241/
https://ncbi.nlm.nih.gov/pubmed/28981686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx782
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