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Circulating dsDNA, endothelial injury, and complement activation in thrombotic microangiopathy and GVHD

Transplant-associated thrombotic microangiopathy (TA-TMA) is a common and poorly recognized complication of hematopoietic stem cell transplantation (HSCT) associated with excessive complement activation, likely triggered by endothelial injury. An important missing piece is the link between endotheli...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gloude, Nicholas J., Khandelwal, Pooja, Luebbering, Nathan, Lounder, Dana T., Jodele, Sonata, Alder, Matthew N., Lane, Adam, Wilkey, Alyss, Lake, Kelly E., Litts, Bridget, Davies, Stella M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714230/
https://ncbi.nlm.nih.gov/pubmed/28705839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-782870
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