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Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner

Akt1 is known to promote non-homologous end-joining (NHEJ)-mediated DNA double-strand break (DSB) repair by stimulation of DNA-PKcs. In the present study, we investigated the effect of Akt1 on homologous recombination (HR)-dependent repair of radiation-induced DSBs in non-small cell lung cancer (NSC...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Mueck, Katharina, Rebholz, Simone, Harati, Mozhgan Dehghan, Rodemann, H. Peter, Toulany, Mahmoud
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713439/
https://ncbi.nlm.nih.gov/pubmed/29156644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112473
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