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Endothelial Mesenchymal Transition in Hypoxic Microvascular Endothelial Cells and Paracrine Induction of Cardiomyocyte Apoptosis Are Mediated via TGFβ(1)/SMAD Signaling

Cardiac remodeling plays a crucial role in the development of heart failure after mycocardial infarction. Besides cardiomyocytes, endothelial cells are recognized to contribute to cardiac remodeling. We now investigated processes of endothelial mesenchymal transition (EndoMT) in microvascular endoth...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sniegon, Isabella, Prieß, Mona, Heger, Jacqueline, Schulz, Rainer, Euler, Gerhild
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713260/
https://ncbi.nlm.nih.gov/pubmed/29088068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112290
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