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PI3K as Mediator of Apoptosis and Contractile Dysfunction in TGFβ(1)-Stimulated Cardiomyocytes
SIMPLE SUMMARY: TGFβ(1) is a growth factor that plays a major role in the remodeling process of the heart by inducing cardiomyocytes dysfunction and apoptosis, as well as fibrosis, thereby restricting heart function. TGFβ(1) mediates its effect via the TGFβ receptor I (ALK5) and the activation of SM...
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| Publicado no: | Biology (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8301398/ https://ncbi.nlm.nih.gov/pubmed/34356525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10070670 |
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