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Molecular docking based screening of a simulated HIF-1 protein model for potential inhibitors
Hypoxia inducible factor-1(HIF-1) is a bHLH-family transcription factor that control genes involved in glucolysis, angiogenesis, migration, as well as invasion factors that are important for tumor progression and metastasis. HIF-1, a hetero dimer of HIF-1α and HIF-1β, binds to the hypoxia responsive...
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| 發表在: | Bioinformation |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Biomedical Informatics
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5712784/ https://ncbi.nlm.nih.gov/pubmed/29225432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630013388 |
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