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Molecular docking based screening of a simulated HIF-1 protein model for potential inhibitors

Hypoxia inducible factor-1(HIF-1) is a bHLH-family transcription factor that control genes involved in glucolysis, angiogenesis, migration, as well as invasion factors that are important for tumor progression and metastasis. HIF-1, a hetero dimer of HIF-1α and HIF-1β, binds to the hypoxia responsive...

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Bibliografski detalji
Izdano u:Bioinformation
Glavni autori: Latha, Mundla Sri, Saddala, Madhu Sudhana
Format: Artigo
Jezik:Inglês
Izdano: Biomedical Informatics 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712784/
https://ncbi.nlm.nih.gov/pubmed/29225432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630013388
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