The SecA protein deeply penetrates into the SecYEG channel during insertion, contacting most channel transmembrane helices and periplasmic regions

The bacterial Sec-dependent system is the major protein-biogenic pathway for protein secretion across the cytoplasmic membrane or insertion of integral membrane proteins into the phospholipid bilayer. The mechanism of SecA-driven protein transport across the SecYEG channel complex has remained contr...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Banerjee, Tithi, Zheng, Zeliang, Abolafia, Jane, Harper, Shelby, Oliver, Donald
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712611/
https://ncbi.nlm.nih.gov/pubmed/28986446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000130
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