High Level of Tobacco Carcinogen–Derived DNA Damage in Oral Cells Is an Independent Predictor of Oral/Head and Neck Cancer Risk in Smokers

Exposure to tobacco-specific nitrosamines (TSNA) and polycyclic aromatic hydrocarbons (PAH) is recognized to play an important role in the development of oral/head and neck squamous cell cancer (HNSCC). We recently reported higher levels of TSNA-associated DNA adducts in the oral cells of smokers wi...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Khariwala, Samir S., Ma, Bin, Ruszczak, Chris, Carmella, Steven G., Lindgren, Bruce, Hatsukami, Dorothy K., Hecht, Stephen S., Stepanov, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712492/
https://ncbi.nlm.nih.gov/pubmed/28679497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0140
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