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A comparative study of the bone regenerative effect of chemically modified RNA encoding BMP-2 or BMP-9

Employing cost-effective biomaterials to deliver chemically modified ribonucleic acid (cmRNA) in a controlled manner addresses the high cost, safety concerns and lower transfection efficiency that exist with protein and gene therapeutic approaches. By eliminating the need for nuclear entry, cmRNA th...

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Detalles Bibliográficos
Publicado en:AAPS J
Main Authors: Khorsand, Behnoush, Elangovan, Satheesh, Hong, Liu, Dewerth, Alexander, Kormann, Michael, Salem, Aliasger K.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712477/
https://ncbi.nlm.nih.gov/pubmed/28074350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-016-0034-8
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