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Effect of Sustained PDGF Non-Viral Gene Delivery on Repair of Tooth-Supporting Bone Defects
Recombinant human platelet-derived growth factor-BB (rhPDGF-BB) promotes soft tissue and bone healing, and is FDA-approved for treatment of diabetic ulcers and periodontal defects. The short half-life of topical rhPDGF-BB protein application necessitates bolus, high-dose delivery. Gene therapy enabl...
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| Pubblicato in: | Gene Ther |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5269540/ https://ncbi.nlm.nih.gov/pubmed/27824330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.73 |
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