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A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects

Gene therapy is a promising strategy to deliver growth factors of interest locally in a sustained fashion and has the potential to overcome barriers to using recombinant protein therapy such as sustainability and cost. Recent studies demonstrate the safety and efficacy of non-viral delivery of plasm...

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Detalhes bibliográficos
Publicado no:Curr Pharm Biotechnol
Main Authors: D'Mello, Sheetal, Elangovan, Satheesh, Hong, Liu, Ross, Ryan D., Sumner, D. Rick, Salem, Aliasger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834972/
https://ncbi.nlm.nih.gov/pubmed/25934975
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