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Alignment-free comparative genomic screen for structured RNAs using coarse-grained secondary structure dot plots

BACKGROUND: Structured non-coding RNAs play many different roles in the cells, but the annotation of these RNAs is lacking even within the human genome. The currently available computational tools are either too computationally heavy for use in full genomic screens or rely on pre-aligned sequences....

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Pubblicato in:BMC Genomics
Autori principali: Kato, Yuki, Gorodkin, Jan, Havgaard, Jakob Hull
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712110/
https://ncbi.nlm.nih.gov/pubmed/29197323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4309-y
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