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Alignment-free comparative genomic screen for structured RNAs using coarse-grained secondary structure dot plots

BACKGROUND: Structured non-coding RNAs play many different roles in the cells, but the annotation of these RNAs is lacking even within the human genome. The currently available computational tools are either too computationally heavy for use in full genomic screens or rely on pre-aligned sequences....

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Kato, Yuki, Gorodkin, Jan, Havgaard, Jakob Hull
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712110/
https://ncbi.nlm.nih.gov/pubmed/29197323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4309-y
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