BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation()()

BACKGROUND: Bone metastasis is common in renal cell carcinoma (RCC), and the lesions are mainly osteolytic. The mechanism of bone destruction in RCC bone metastasis is unknown. METHODS: We used a direct intrafemur injection of mice with bone-derived 786-O RCC cells (Bo-786) as an in vivo model to st...

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Publicado en:Neoplasia
Autores principales: Pan, Tianhong, Lin, Song-Chang, Yu, Kai-Jie, Yu, Guoyu, Song, Jian H., Lewis, Valerae O., Bird, Justin E., Moon, Bryan, Lin, Patrick P., Tannir, Nizar M., Jonasch, Eric, Wood, Christopher G, Gallick, Gary E., Yu-Lee, Li-Yuan, Lin, Sue-Hwa, Satcher, Robert L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2017
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711998/
https://ncbi.nlm.nih.gov/pubmed/29190493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.11.002
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