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Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

Mast cells are implicated as detrimental players in inflammatory lung diseases, particularly asthma. Mast cells respond to activating stimuli by releasing a wide panel of pro-inflammatory compounds that can contribute profoundly to the pathology, and there is currently an unmet need for strategies t...

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Pubblicato in:Front Immunol
Autori principali: Paivandy, Aida, Sandelin, Martin, Igelström, Helena, Landelius, Per, Janson, Christer, Melo, Fabio R., Pejler, Gunnar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711769/
https://ncbi.nlm.nih.gov/pubmed/29230220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01645
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