Alcohol feeding in mice promotes colonic hyperpermeability and changes in colonic organoid stem cell fate

BACKGROUND: Alcohol increases intestinal permeability to pro-inflammatory microbial products that promote liver disease, even after a period of sobriety. We sought to test the hypothesis that alcohol affects intestinal stem cells using an in vivo model and ex vivo organoids generated from jejunum an...

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Vydáno v:Alcohol Clin Exp Res
Hlavní autoři: Forsyth, Christopher B., Shaikh, Maliha, Bishehsari, Faraz, Swanson, Garth, Voigt, Robin M., Dodiya, Hemraj, Wilkinson, Peter, Samelco, Beata, Song, Shiwen, Keshavarzian, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711563/
https://ncbi.nlm.nih.gov/pubmed/28992396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13519
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