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Alcohol Reduces Arterial Remodeling by Inhibiting Sonic Hedgehog-Stimulated Sca1(+) Progenitor Stem Cell Expansion

BACKGROUND: Cell and molecular mechanisms mediating the cardiovascular effects of alcohol are not fully understood. Our aim was to determine the effect of moderate Ethanol (EtOH) on Sonic Hedgehog (SHh) signaling in regulating possible Sca1(+) progenitor stem cell involvement during pathologic arter...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Fitzpatrick, Emma, Han, Xu, Liu, Weimin, Corcoran, Eoin, Burtenshaw, Denise, Morrow, David, Helt, Jay-Christian, Cahill, Paul A., Redmond, Eileen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711561/
https://ncbi.nlm.nih.gov/pubmed/28921619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13499
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