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Morphine withdrawal increases brain derived neurotrophic factor precursor

Morphine has been shown to increase the expression of brain-derived neurotrophic factor (BDNF) in the brain. However, little is known about the effect of morphine withdrawal on BDNF and its precursor protein, or proBDNF, which induces neuronal apoptosis. In this work, we examined whether BDNF and pr...

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Detalhes bibliográficos
Publicado no:Neurotox Res
Main Authors: Bachis, Alessia, Campbell, Lee A., Jenkins, Kierra, Wenzel, Erin, Mocchetti, Italo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711538/
https://ncbi.nlm.nih.gov/pubmed/28776309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-017-9788-8
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