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Human Immunodeficiency Virus Type 1 Alters Brain-Derived Neurotrophic Factor Processing in Neurons

The molecular mechanisms leading to synaptic simplification and neuronal apoptosis in human immunodeficiency virus type 1 (HIV-1)-positive subjects are unknown. The HIV protein gp120 reduced the length of neuronal processes similarly to the proneurotrophin pro–brain-derived neurotrophic factor (proB...

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Detalhes bibliográficos
Main Authors: Bachis, Alessia, Avdoshina, Valeriya, Zecca, Luigi, Parsadanian, Maia, Mocchetti, Italo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408006/
https://ncbi.nlm.nih.gov/pubmed/22787033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0865-12.2012
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