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Prevention of renal apoB retention is protective against diabetic nephropathy: role of TGF-β inhibition

Animal studies demonstrate that hyperlipidemia and renal lipid accumulation contribute to the pathogenesis of diabetic nephropathy (DN). We previously demonstrated that renal lipoproteins colocalize with biglycan, a renal proteoglycan. The purpose of this study was to determine whether prevention of...

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Pubblicato in:J Lipid Res
Autori principali: Wilson, Patricia G., Thompson, Joel C., Yoder, Meghan H., Charnigo, Richard, Tannock, Lisa R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711490/
https://ncbi.nlm.nih.gov/pubmed/28912302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078204
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