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Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis

As one of the virulence factors of Bacillus anthracis, lethal toxin (LT) induces various pathogenic responses including the suppression of the coagulation system. In this study, we observed that LT markedly increased the circulating soluble P-selectin (sP-sel) levels and microparticle (MP) count in...

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Publicado en:Virulence
Autores principales: Sun, Der-Shan, Chang, Yao-Wen, Kau, Jyh-Hwa, Huang, Hsin-Hsien, Ho, Pei-Hsun, Tzeng, Yin-Jeh, Chang, Hsin-Hou
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711406/
https://ncbi.nlm.nih.gov/pubmed/28102766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1282027
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