Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis

As one of the virulence factors of Bacillus anthracis, lethal toxin (LT) induces various pathogenic responses including the suppression of the coagulation system. In this study, we observed that LT markedly increased the circulating soluble P-selectin (sP-sel) levels and microparticle (MP) count in...

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Udgivet i:Virulence
Main Authors: Sun, Der-Shan, Chang, Yao-Wen, Kau, Jyh-Hwa, Huang, Hsin-Hsien, Ho, Pei-Hsun, Tzeng, Yin-Jeh, Chang, Hsin-Hou
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711406/
https://ncbi.nlm.nih.gov/pubmed/28102766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1282027
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