Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis

As one of the virulence factors of Bacillus anthracis, lethal toxin (LT) induces various pathogenic responses including the suppression of the coagulation system. In this study, we observed that LT markedly increased the circulating soluble P-selectin (sP-sel) levels and microparticle (MP) count in...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Sun, Der-Shan, Chang, Yao-Wen, Kau, Jyh-Hwa, Huang, Hsin-Hsien, Ho, Pei-Hsun, Tzeng, Yin-Jeh, Chang, Hsin-Hou
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711406/
https://ncbi.nlm.nih.gov/pubmed/28102766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1282027
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