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Suppressive Effects of Anthrax Lethal Toxin on Megakaryopoiesis
Anthrax lethal toxin (LT) is a major virulence factor of Bacillus anthracis. LT challenge suppresses platelet counts and platelet function in mice, however, the mechanism responsible for thrombocytopenia remains unclear. LT inhibits cellular mitogen-activated protein kinases (MAPKs), which are vital...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605335/ https://ncbi.nlm.nih.gov/pubmed/23555687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059512 |
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