Suppressive Effects of Anthrax Lethal Toxin on Megakaryopoiesis

Anthrax lethal toxin (LT) is a major virulence factor of Bacillus anthracis. LT challenge suppresses platelet counts and platelet function in mice, however, the mechanism responsible for thrombocytopenia remains unclear. LT inhibits cellular mitogen-activated protein kinases (MAPKs), which are vital...

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Detalhes bibliográficos
Main Authors: Chen, Po-Kong, Chang, Hsin-Hou, Lin, Guan-Ling, Wang, Tsung-Pao, Lai, Yi-Ling, Lin, Ting-Kai, Hsieh, Ming-Chun, Kau, Jyh-Hwa, Huang, Hsin-Hsien, Hsu, Hui-Ling, Liao, Chi-Yuan, Sun, Der-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605335/
https://ncbi.nlm.nih.gov/pubmed/23555687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059512
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