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The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells

The S-acyltransferase zDHHC2 mediates dynamic S-acylation of PSD95 and AKAP79/150, which impacts synaptic targeting of AMPA receptors. zDHHC2 is responsive to synaptic activity and catalyses the increased S-acylation of PSD95 that occurs following action potential blockade or application of ionotrop...

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Détails bibliographiques
Publié dans:Mol Cell Neurosci
Auteurs principaux: Salaun, Christine, Ritchie, Louise, Greaves, Jennifer, Bushell, Trevor J., Chamberlain, Luke H.
Format: Artigo
Langue:Inglês
Publié: Academic Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711357/
https://ncbi.nlm.nih.gov/pubmed/28768144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2017.07.007
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