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Sevoflurane causes greater QTc interval prolongation in chronically hyperglycemic patients than in normoglycemic patients

QTc interval prolongation is a serious diabetic complication and increases mortality rate. Hyperglycemia inhibits the rapid component of delayed rectifier potassium channel currents (Ikr) and prolongs the QTc interval on electrocardiograms. Sevoflurane also inhibits the Ikr and causes QTc interval p...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Kimura, Seishi, Nakao, Shinichi, Kitaura, Atsuhiro, Iwamoto, Tatushige, Houri, Kei, Matsushima, Mayuka, Hamasaki, Shinichi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711029/
https://ncbi.nlm.nih.gov/pubmed/29194447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188555
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