Chronic myelomonocytic leukemia with double-mutations in DNMT3A and FLT3-ITD treated with decitabine and sorafenib

Chronic myelomonocytic leukemia (CMML) is a heterogeneous neoplastic hematologic disorder with worse overall survival. Half of CMML have mutations, but case with concomitant mutations of DNA methyltransferase 3A (DNMT3A) and Internal tandem duplications of the juxtamembrane domain of FLT3 (FLT3-ITD)...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Gu, Jia, Wang, Zhiqiong, Xiao, Min, Mao, Xia, Zhu, Li, Wang, Ying, Huang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Bedside to Bench Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710697/
https://ncbi.nlm.nih.gov/pubmed/28102729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1281491
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