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Cabozantinib inhibits tumor growth and metastasis of a patient-derived xenograft model of papillary renal cell carcinoma with MET mutation

MET plays an important role in the development and progression of papillary renal cell carcinoma (pRCC). Evaluation of efficacy of MET inhibitors against pRCC has been hampered by limited preclinical models depicting MET abnormalities. We established a new patient-derived xenograft (PDX) model of pR...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Zhao, Hongjuan, Nolley, Rosalie, Chan, Andy M. W., Rankin, Erinn B., Peehl, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710673/
https://ncbi.nlm.nih.gov/pubmed/27715452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1219816
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