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What Is Wrong with Pertussis Vaccine Immunity?: The Problem of Waning Effectiveness of Pertussis Vaccines

Pertussis is resurgent in some countries, particularly those in which children receive acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic studies show that, whereas whole-cell pertussis (wP) vaccines orient the immune system toward Th1/Th17 responses, acellula...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Perspect Biol
Main Authors: Burdin, Nicolas, Handy, Lori Kestenbaum, Plotkin, Stanley A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710106/
https://ncbi.nlm.nih.gov/pubmed/28289064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a029454
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