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What Is Wrong with Pertussis Vaccine Immunity?: Inducing and Recalling Vaccine-Specific Immunity

The high incidence of pertussis in vaccinated adolescents suggests the failing of immune memory. We argue that acellular pertussis vaccines generate memory cells that are effectively reactivated by boosters better than by Bordetella pertussis exposure. We propose that there are two main causes. One...

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Publié dans:Cold Spring Harb Perspect Biol
Auteurs principaux: Eberhardt, Christiane S., Siegrist, Claire-Anne
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710108/
https://ncbi.nlm.nih.gov/pubmed/28289058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a029629
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